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POU5F1B Antibody (internal region, near C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q06416 |
| Other Accession | NP_001153014.1, 5462, 5460 |
| Predicted | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 38588 Da |
| Gene ID | 5462 |
|---|---|
| Other Names | Putative POU domain, class 5, transcription factor 1B, Oct4-pg1, Octamer-binding protein 3-like, Octamer-binding transcription factor 3-like, POU5F1B |
| Dilution | E~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | POU5F1B Antibody (internal region, near C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | POU5F1B |
|---|---|
| Function | Shows weak transcriptional activator activity. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00530, ECO:0000269|PubMed:18949397} Cytoplasm |
| Tissue Location | Detected in epithelial cells of the prostate (at protein level) (PubMed:20017164). Detected at the mRNA level in several cancer tissues (breast, uterine cervix, lung, thyroid gland, esophagus, colon, urinary bladder, and glioma) (PubMed:16229821, PubMed:21341266) |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to crossreact to the almost identical OCT4 / POU5F1 (GeneID 5460).
References
The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1. Panagopoulos I, Möller E, Collin A, Mertens F, Oncology reports 2008 Nov 20 (5): 1029-33. PMID: 18949397
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