Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
DNAH8 (aa107 -117) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q96JB1 |
| Other Accession | NP_001362.2, 1769 |
| Predicted | Human, Rabbit, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 514664 Da |
| Gene ID | 1769 |
|---|---|
| Other Names | Dynein heavy chain 8, axonemal, Axonemal beta dynein heavy chain 8, Ciliary dynein heavy chain 8, DNAH8 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DNAH8 (aa107 -117) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DNAH8 (HGNC:2952) |
|---|---|
| Function | Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. |
| Cellular Location | Cytoplasm, cytoskeleton, flagellum axoneme. Cytoplasm {ECO:0000250|UniProtKB:Q91XQ0}. Note=Detected in sperm tail, with almost exclusive localization to the principal piece. Also detected in the cytoplasm of primary spermatocytes. {ECO:0000250|UniProtKB:Q91XQ0} |
| Tissue Location | Expressed in spermatozoa (at protein level). Not detected in airway epithelial cells (at protein level) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Human V-ATPase gene can protect or predispose the host to pulmonary tuberculosis. Capparelli R, Palumbo D, Iannaccone M, Iannelli D, Genes and immunity 2009 Oct 10 (7): 641-6. PMID: 19536151
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
