PPPDE1 / PNAS4 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9BSY9 |
Other Accession | NP_057160.2, 51029, 78825 (mouse), 289277 (rat) |
Reactivity | Human |
Predicted | Mouse, Rat, Pig, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 21444 Da |
Gene ID | 51029 |
---|---|
Other Names | Desumoylating isopeptidase 2, DeSI-2, 3.4.-.-, PPPDE peptidase domain-containing protein 1, Protein FAM152A, DESI2, C1orf121, FAM152A, PPPDE1 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PPPDE1 / PNAS4 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DESI2 |
---|---|
Function | Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization (PubMed:28483520). Exhibits palmitoyl protein thioesterase (S- depalmitoylation) activity towards synthetic substrates 4- methylumbelliferyl-6-S-palmitoyl-beta-D-glucopyranoside and S- depalmitoylation probe 5 (DPP-5) (PubMed:35427157). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q9D291}. |
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Provided below are standard protocols that you may find useful for product applications.
References
A novel pro-apoptosis gene PNAS4 that induces apoptosis in A549 human lung adenocarcinoma cells and inhibits tumor growth in mice. Yan F, Gou L, Yang J, Chen L, Tong A, Tang M, Yuan Z, Yao S, Zhang P, Wei Y, Biochimie 2009 Apr 91 (4): 502-7. PMID: 19133312
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