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MOBKL3 (aa137-151) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, E |
|---|---|
| Primary Accession | Q9Y3A3 |
| Other Accession | NP_056202.2, NP_955776.1, NP_001094289.1, 25843, 19070 (mouse), 171050 (rat) |
| Reactivity | Human, Mouse, Rat |
| Predicted | Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 26032 Da |
| Gene ID | 25843 |
|---|---|
| Other Names | MOB-like protein phocein, 2C4D, Class II mMOB1, Mob1 homolog 3, Mob3, Mps one binder kinase activator-like 3, Preimplantation protein 3, MOB4, MOB3, MOBKL3, PHOCN, PREI3 |
| Dilution | WB~~1:1000 IHC~~1:100~500 E~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MOBKL3 (aa137-151) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MOB4 (HGNC:17261) |
|---|---|
| Function | Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation. |
| Cellular Location | Cytoplasm, perinuclear region. Membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Note=In a perinuclear punctate pattern. Associated with membranes and the Golgi stacks |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize all three reported isoforms (NP_056202.2; NP_955776.1; NP_001094289.1).
References
Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1. Hirabayashi S, Nakagawa K, Sumita K, Hidaka S, Kawai T, Ikeda M, Kawata A, Ohno K, Hata Y, Oncogene 2008 Jul 27 (31): 4281-92. PMID: 18362890
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