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thyroid peroxidase Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, E |
|---|---|
| Primary Accession | P07202 |
| Other Accession | NP_000538.3, NP_783650.1, NP_783652.1, NP_783653.1, 7173 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 102963 Da |
| Gene ID | 7173 |
|---|---|
| Other Names | Thyroid peroxidase, TPO, 1.11.1.8, TPO |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | thyroid peroxidase Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TPO (HGNC:12015) |
|---|---|
| Function | Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize reported isoforms a (NP_000538.3) and e (NP_783653.1).
References
Antibodies to thyroid peroxidase arise spontaneously with age in NOD.H-2h4 mice and appear after thyroglobulin antibodies. Chen CR, Hamidi S, Braley-Mullen H, Nagayama Y, Bresee C, Aliesky HA, Rapoport B, McLachlan SM. Endocrinology. 2010 Sep;151(9):4583-93. PMID: 20573721
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