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ARPC1A Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q92747 |
| Other Accession | NP_006400.2, NP_001177925.1, 10552, 56443 (mouse), 81824 (rat) |
| Reactivity | Human |
| Predicted | Mouse, Rat, Pig |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 41569 Da |
| Gene ID | 10552 |
|---|---|
| Other Names | Actin-related protein 2/3 complex subunit 1A, SOP2-like protein, ARPC1A, SOP2L |
| Dilution | WB~~1:1000 E~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ARPC1A Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ARPC1A |
|---|---|
| Synonyms | SOP2L |
| Function | Probably functions as a component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. |
| Cellular Location | Cytoplasm, cytoskeleton. Nucleus {ECO:0000250|UniProtKB:Q8AVT9} |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize both reported isoforms (NP_006400.2; NP_001177925.1). No cross-reactiviry expected with ARPC1B.
References
Characterization of the 7q21-q22 amplicon identifies ARPC1A, a subunit of the Arp2/3 complex, as a regulator of cell migration and invasion in pancreatic cancer. Laurila E, Savinainen K, Kuuselo R, Karhu R, Kallioniemi A. Genes Chromosomes Cancer. 2009 Apr;48(4):330-9. PMID: 19145645
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