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GEM (aa34-46) Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - GEM (aa34-46) Antibody (internal region) AF3756a
    HEK293 lysate overexpressing full-length Human GEM (HA tagged), mock-transfected HEK293 (EV) and HEK293 transiently expressing GEM-related genes (Rem, Rem2L and Rad) probed with AF3756a (1ug/ml). The same lysates probed with anti-HA tag antibody in the lower panel.
    detail
  • WB - GEM (aa34-46) Antibody (internal region) AF3756a
    AF3756a (1 µg/ml) staining of Human Spleen lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P55040
Other Accession NP_005252.1, 2669
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 33949 Da
Additional Information
Gene ID 2669
Other Names GTP-binding protein GEM, GTP-binding mitogen-induced T-cell protein, RAS-like protein KIR, GEM, KIR
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGEM (aa34-46) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GEM
Synonyms KIR
Function Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
Cellular Location Cell membrane; Peripheral membrane protein; Cytoplasmic side
Tissue Location Most abundant in thymus, spleen, kidney, lung, and testis. Less abundant in heart, brain, liver and skeletal muscle
Research Areas
Citations (0)
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Background

Reported variants represent identical protein: NP_005252.1, NP_859053.1

References

A systemic network for Chlamydia pneumoniae entry into human cells. Wang A, Johnston SC, Chou J, Dean D. J Bacteriol. 2010 Jun;192(11):2809-15. PMID: 20233927

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$ 341.00
Cat# AF3756a
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Availability: 7-10 days
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