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Goat Anti-DMRT2 Antibody (C Terminus)
Purified Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC, E |
|---|---|
| Primary Accession | Q9Y5R5 |
| Other Accession | 226049(mouse), 309430(rat), NP_006548.1, NP_870987.2 |
| Reactivity | Human |
| Predicted | Human, Mouse, Rat |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 |
| Calculated MW | 61814 Da |
| Gene ID | 10655 |
|---|---|
| Other Names | DMRT2; doublesex and mab-3 related transcription factor 2; OTTHUMP00000020964; OTTHUMP00000020965; OTTHUMP00000020966; OTTHUMP00000020967; terra-like protein |
| Dilution | IHC~~1:100~500 E~~N/A |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | Peptide with sequence C-KRPSSAITRVSQ, from the C Terminus of the protein sequence according to NP_006548.1; NP_870987.2. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-DMRT2 Antibody (C Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DMRT2 |
|---|---|
| Synonyms | DSXL2 |
| Function | Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}. |
| Tissue Location | Expressed in testis, kidney and skeletal muscle. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Dmrt2 and Pax3 double-knockout mice show severe defects in embryonic myogenesis. Seo KW. Comparative medicine 2007 Oct 57 (5): 460-8.
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