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Goat Anti-IL13RA2 Antibody (internal region)
Purified Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q14627 |
| Other Accession | NP_000631.1 |
| Reactivity | Human |
| Predicted | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 |
| Calculated MW | 44176 Da |
| Gene ID | 3598 |
|---|---|
| Other Names | IL13RA2; interleukin 13 receptor, alpha 2; CD213A2; CT19; IL-13R; IL13BP; IL-13 receptor subunit alpha-2; IL-13R subunit alpha-2; IL-13R-alpha-2; IL-13RA2; cancer/testis antigen 19; interleukin 13 binding protein; interleukin 13 receptor alpha 2 chain; in |
| Dilution | WB~~1:1000 E~~N/A |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | Peptide with sequence C-DLNKGIEAKIHT , from the internal region of the protein sequence according to NP_000631.1. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-IL13RA2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IL13RA2 |
|---|---|
| Synonyms | IL13R |
| Function | Cell surface receptor that plays a role in the regulation of IL-13-mediated responses (PubMed:11861389, PubMed:17030238). Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation (PubMed:11861389, PubMed:17030238). Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1 (PubMed:16327802). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
IL-13 antibodies influence IL-13 clearance in humans by modulating scavenger activity of IL-13Rα2. Kasaian MT, Raible D, Marquette K, Cook TA, Zhou S, Tan XY, Tchistiakova L. Journal of immunology (Baltimore, Md. : 1950) 2011 Jul 187 (1): 561-9.
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