Goat Anti-ATF1 Antibody (N Terminus)
Purified Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | P18846 |
| Other Accession | NP_005162.1, 466 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 29233 Da |
| Gene ID | 466 |
|---|---|
| Other Names | ATF1; activating transcription factor 1; EWS-ATF1; FUS/ATF-1; TREB36; cAMP-dependent transcription factor ATF-1; cyclic AMP-dependent transcription factor ATF-1 |
| Dilution | WB~~1:1000 E~~N/A |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | Peptide with sequence EDSHKSTTSETAPQ-C, from the N Terminus of the protein sequence according to NP_005162.1. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-ATF1 Antibody (N Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ATF1 |
|---|---|
| Function | This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. |
| Cellular Location | Nucleus. |

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Provided below are standard protocols that you may find useful for product applications.
References
Huang GL, Guo HQ, Yang F, Liu OF, Li BB, Liu XY, Lu Y, He ZW.
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