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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-TCF3 / ITF1, Biotinylated Antibody
Goat anti-TCF3 / ITF1, Biotinylated Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
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Application 
| WB, IHC, Pep-ELISA |
|---|---|
| Primary Accession | P15923 |
| Other Accession | NP_003191.1 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | TCF3 |
| Calculated MW | 67600 Da |
| Gene ID | 6929 |
|---|---|
| Other Names | TCF3; transcription factor 3; E2A; E47; ITF1; TCF-3; VDIR; bHLHb21; NOL1-TCF3 fusion; VDR interacting repressor; class B basic helix-loop-helix protein 21; helix-loop-helix protein HE47; immunoglobulin transcription factor 1; kappa-E2-binding factor; nega |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | This antibody is expected to recognize reported isoform E12 (NP_003191.1) only. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-TCF3 / ITF1, Biotinylated Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TCF3 |
|---|---|
| Synonyms | BHLHB21, E2A, ITF1 |
| Function | Transcriptional regulator involved in the initiation of neuronal differentiation and mesenchymal to epithelial transition (By similarity). Heterodimers between TCF3 and tissue-specific basic helix- loop-helix (bHLH) proteins play major roles in determining tissue- specific cell fate during embryogenesis, like muscle or early B-cell differentiation (By similarity). Together with TCF15, required for the mesenchymal to epithelial transition (By similarity). Dimers bind DNA on E-box motifs: 5'-CANNTG-3' (By similarity). Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer (PubMed:2493990). Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region (By similarity). |
| Cellular Location | Nucleus. |
Research Areas
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Application Protocols
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$ 341.00
Cat# AF4407a
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