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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-PTGIS / CYP8A1 (aa248-258) Antibody
Goat anti-PTGIS / CYP8A1 (aa248-258) Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB, Pep-ELISA |
|---|---|
| Primary Accession | Q16647 |
| Other Accession | NP_000952.1 |
| Reactivity | Human, Pig |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | PTGIS |
| Calculated MW | 57104 Da |
| Gene ID | 5740 |
|---|---|
| Other Names | PTGIS; prostaglandin I2 (prostacyclin) synthase; CYP8; CYP8A1; PGIS; PTGI; cytochrome P450, family 8, subfamily A, polypeptide 1; prostacyclin synthase; prostaglandin I2 synthase |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-PTGIS / CYP8A1 (aa248-258) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PTGIS |
|---|---|
| Synonyms | CYP8, CYP8A1 |
| Function | Catalyzes the biosynthesis and metabolism of eicosanoids. Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2), a potent mediator of vasodilation and inhibitor of platelet aggregation (PubMed:18032380, PubMed:25623425, PubMed:12372404, PubMed:15115769). Additionally, displays dehydratase activity, toward hydroperoxyeicosatetraenoates (HPETEs), especially toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)- HPETE) (PubMed:17459323). |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q29626}; Single-pass membrane protein |
| Tissue Location | Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 341.00
Cat# AF4414a
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