Goat anti-ILF2 / NF45, Biotinylated Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, Pep-ELISA |
---|---|
Primary Accession | Q12905 |
Other Accession | NP_004506.2, NP_001254738.1 |
Reactivity | Human, Mouse, Rat, Dog |
Host | Goat |
Clonality | Polyclonal |
Clone Names | ILF2 |
Calculated MW | 43062 Da |
Gene ID | 3608 |
---|---|
Other Names | ILF2; interleukin enhancer binding factor 2; NF45; PRO3063; interleukin enhancer binding factor 2, 45kD; interleukin enhancer binding factor 2, 45kDa; nuclear factor of activated T-cells, 45-kDa |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Immunogen | This antibody is expected to recognize both reported isoforms (NP_004506.2; NP_001254738.1). |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat anti-ILF2 / NF45, Biotinylated Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ILF2 |
---|---|
Synonyms | NF45 |
Function | Chromatin-interacting protein that forms a stable heterodimer with interleukin enhancer-binding factor 3/ILF3 and plays a role in several biological processes including transcription, innate immunity or cell growth (PubMed:18458058, PubMed:31212927). Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus. Together with ILF3, forms an RNA-binding complex that is required for mitotic progression and cytokinesis by regulating the expression of a cluster of mitotic genes. Mechanistically, competes with STAU1/STAU2-mediated mRNA decay (PubMed:32433969). Also plays a role in the inhibition of various viruses including Japanese encephalitis virus or enterovirus 71. |
Cellular Location | Nucleus, nucleolus. Cytoplasm. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs |
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