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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-TRPV5, Biotinylated Antibody
Goat anti-TRPV5, Biotinylated Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, IF, ICC, Pep-ELISA |
|---|---|
| Primary Accession | Q9NQA5 |
| Other Accession | NP_062815.3 |
| Reactivity | Human, Mouse, Rat, Pig, Dog, Bovine |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | TRPV5 |
| Calculated MW | 82562 Da |
| Gene ID | 56302 |
|---|---|
| Other Names | TRPV5; transient receptor potential cation channel subfamily V member 5; CAT2; ECAC1; OTRPC3; calcium transport protein 2; calcium transporter 2; epithelial calcium channel 1; osm-9-like TRP channel 3; transient receptor potential cation channel, subfamil |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-TRPV5, Biotinylated Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRPV5 |
|---|---|
| Synonyms | ECAC1 {ECO:0000303|PubMed:10945469} |
| Function | Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubules (By similarity). The channel is activated by low internal calcium level and the current exhibits an inward rectification (PubMed:11549322, PubMed:18768590). A Ca(2+)-dependent feedback regulation includes fast channel inactivation and slow current decay (By similarity). Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating (By similarity). |
| Cellular Location | Apical cell membrane; Multi-pass membrane protein. Note=Colocalized with S100A10 and ANAX2 along the apical domain of kidney distal tubular cells (By similarity) The expression of the glycosylated form in the cell membrane is increased in the presence of WNK3 (PubMed:18768590) {ECO:0000250|UniProtKB:P69744, ECO:0000269|PubMed:18768590} |
| Tissue Location | Expressed at high levels in kidney, small intestine and pancreas, and at lower levels in testis, prostate, placenta, brain, colon and rectum. |
Research Areas
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Application Protocols
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$ 341.00
Cat# AF4430a
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