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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-AP3B1 / HPS Antibody
Goat anti-AP3B1 / HPS Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
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- BACKGROUND
Application 
| FC, Pep-ELISA |
|---|---|
| Primary Accession | O00203 |
| Other Accession | NP_003655 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | AP3B1 |
| Calculated MW | 121320 Da |
| Gene ID | 8546 |
|---|---|
| Other Names | AP3B1; PE; HPS; HPS2; ADTB3; ADTB3A; adaptor-related protein complex 3, beta 1 subunit; beta3A-adaptin; AP-3 complex beta-3A subunit |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-AP3B1 / HPS Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AP3B1 |
|---|---|
| Synonyms | ADTB3A |
| Function | Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |
| Cellular Location | Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex |
| Tissue Location | Ubiquitously expressed. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 341.00
Cat# AF4492a
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