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Goat anti-KCNN4 / KCa3.1 Antibody

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, FC, Pep-ELISA
Primary Accession O15554
Other Accession NP_002241.1
Reactivity Human, Mouse, Rat, Dog
Host Goat
Clonality Polyclonal
Clone Names KCNN4
Calculated MW 47696 Da
Additional Information
Gene ID 3783
Other Names KCNN4; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; IK1; IKCA1; KCA4; KCa3.1; SK4; hIKCa1; hKCa4; hSK4; intermediate conductance calcium-activated potassium channel protein 1; putative erythrocyte intermediate
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat anti-KCNN4 / KCa3.1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNN4
Synonyms IK1, IKCA1, KCA4, SK4
Function Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells (PubMed:17157250, PubMed:18796614). Plays a role in the late stages of EGF-induced macropinocytosis (PubMed:24591580).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Widely expressed in non-excitable tissues.
Research Areas
Citations (0)
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$ 341.00
Cat# AF4517a
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Availability: 7-10 days
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