Goat anti-KCNN4 / KCa3.1 Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IF, FC, Pep-ELISA |
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Primary Accession | O15554 |
Other Accession | NP_002241.1 |
Reactivity | Human, Mouse, Rat, Dog |
Host | Goat |
Clonality | Polyclonal |
Clone Names | KCNN4 |
Calculated MW | 47696 Da |
Gene ID | 3783 |
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Other Names | KCNN4; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; IK1; IKCA1; KCA4; KCa3.1; SK4; hIKCa1; hKCa4; hSK4; intermediate conductance calcium-activated potassium channel protein 1; putative erythrocyte intermediate |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat anti-KCNN4 / KCa3.1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KCNN4 |
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Synonyms | IK1, IKCA1, KCA4, SK4 |
Function | Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells (PubMed:17157250, PubMed:18796614). Plays a role in the late stages of EGF-induced macropinocytosis (PubMed:24591580). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Widely expressed in non-excitable tissues. |
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