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Goat anti-GP91-PHOX / NOX2 Antibody

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, Pep-ELISA
Primary Accession P04839
Other Accession NP_000388.2
Reactivity Human, Mouse, Rat, Pig, Dog, Bovine
Host Goat
Clonality Polyclonal
Clone Names CYBB
Calculated MW 65336 Da
Additional Information
Gene ID 1536
Other Names CYBB; cytochrome b-245, beta polypeptide; CGD; GP91-1; GP91-PHOX; GP91PHOX; NOX2; p91-PHOX; CGD91-phox; NADPH oxidase 2; cytochrome b(558) subunit beta; cytochrome b-245 heavy chain; cytochrome b558 subunit beta; heme-binding membrane glycoprotein gp91pho
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat anti-GP91-PHOX / NOX2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYBB (HGNC:2578)
Synonyms NOX2
Function Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
Cellular Location Cell membrane; Multi-pass membrane protein. Note=As unassembled monomer may localize to the endoplasmic reticulum
Tissue Location Detected in neutrophils (at protein level).
Research Areas
Citations (0)
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$ 341.00
Cat# AF4526a
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Availability: 7-10 days
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