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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-EDF1 / MBF1 Antibody
Goat anti-EDF1 / MBF1 Antibody
Peptide-affinity purified goat antibody
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- CITATIONS
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Application 
| WB, IHC, IF, FC, Pep-ELISA |
|---|---|
| Primary Accession | O60869 |
| Other Accession | NP_003783.1, NP_694880.1, NP_001268226.1, NP_001268227.1, NP_001268228.1 |
| Reactivity | Human, Mouse, Rat |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | EDF1 |
| Calculated MW | 16369 Da |
| Gene ID | 8721 |
|---|---|
| Other Names | EDF1; MBF1; EDF-1; MGC9058; endothelial differentiation-related factor 1; multiprotein bridging factor 1 |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-EDF1 / MBF1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EDF1 |
|---|---|
| Function | Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. |
| Cellular Location | Cytoplasm. Nucleus. Note=Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin |
| Tissue Location | Expressed in brain, liver, lung, kidney and heart (at protein level). Ubiquitously expressed. More abundant in heart, pancreas, liver, intestine and adipose tissues |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 341.00
Cat# AF4532a
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