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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-PRKAB2 Antibody
Goat anti-PRKAB2 Antibody
Peptide-affinity purified goat antibody
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- BACKGROUND
Application 
| IHC, IF, FC, Pep-ELISA |
|---|---|
| Primary Accession | O43741 |
| Other Accession | NP_005390.1 |
| Reactivity | Human, Mouse, Rat, Bovine |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | PRKAB2 |
| Calculated MW | 30302 Da |
| Gene ID | 5565 |
|---|---|
| Other Names | PRKAB2 ; protein kinase, AMP-activated, beta 2 non-catalytic subunit ; MGC61468; 5'-AMP-activated protein kinase, beta-2 subunit; AMP-activated protein kinase beta 2 non-catalytic subunit; AMPK beta 2; AMPK beta-2 chain |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-PRKAB2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PRKAB2 |
|---|---|
| Function | Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C- terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 341.00
Cat# AF4533a
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