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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-Peroxiredoxin 1 Rabbit Monoclonal Antibody
KD-Validated Anti-Peroxiredoxin 1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q06830 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB 2120 |
| Calculated MW | Predicted, 22 kDa , observed, 22 kDa |
| Gene Name | PRDX1 |
| Aliases | PRDX1; Peroxiredoxin 1; NKEFA; PAGA; Thioredoxin-Dependent Peroxide Reductase; Natural Killer Cell-Enhancing Factor A; Proliferation-Associated Gene Protein; Thioredoxin-Dependent Peroxiredoxin 1; Thioredoxin Peroxidase; Peroxiredoxin-1; NKEF-A; TDPX2; PAGB; PAG; Epididymis Secretory Sperm Binding Protein; Natural Killer-Enhancing Factor A; Proliferation-Associated Gene A; EC 1.11.1.24; EC 1.11.1.15; EC 1.11.1; MSP23; PRX1; PRXI |
| Immunogen | A synthesized peptide derived from human PRDX1 |
| Gene ID | 5052 |
|---|---|
| Other Names | Peroxiredoxin-1, 1.11.1.24, Natural killer cell-enhancing factor A, NKEF-A, Proliferation-associated gene protein, PAG, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2, Thioredoxin-dependent peroxiredoxin 1, PRDX1, PAGA, PAGB, TDPX2 |
| Name | PRDX1 |
|---|---|
| Synonyms | PAGA, PAGB, TDPX2 |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (PubMed:9497357). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity). |
| Cellular Location | Cytoplasm. Melanosome Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI1065
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