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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-ACSL4 Rabbit Monoclonal Antibody
KD-Validated Anti-ACSL4 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | O60488 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB2960 |
| Calculated MW | Predicted, 79 kDa, observed, 73 kDa |
| Gene Name | ACSL4 |
| Aliases | ACSL4; Acyl-CoA Synthetase Long Chain Family Member 4; LACS4; ACS4; FACL4; Fatty-Acid-Coenzyme A Ligase, Long-Chain 4; Long-Chain Fatty-Acid-Coenzyme A Ligase 4; Long-Chain-Fatty-Acid--CoA Ligase 4; Long-Chain Acyl-CoA Synthetase 4; Lignoceroyl-CoA Synthase; Arachidonate--CoA Ligase; EC 6.2.1.3; MRX63; MRX68; Mental Retardation, X-Linked 63; Mental Retardation, X-Linked 68; Acyl-CoA Synthetase 4; EC 6.2.1.15; XLID63; LACS 4 |
| Immunogen | A synthesized peptide derived from ACSL4 |
| Gene ID | 2182 |
|---|---|
| Other Names | Long-chain-fatty-acid--CoA ligase 4, 6.2.1.3, Arachidonate--CoA ligase, 6.2.1.15, Long-chain acyl-CoA synthetase 4, LACS 4, ACSL4, ACS4, FACL4, LACS4 |
| Name | ACSL4 |
|---|---|
| Synonyms | ACS4, FACL4, LACS4 |
| Function | Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:21242590, PubMed:22633490, PubMed:24269233). Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590). Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose- stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity). Modulates prostaglandin E2 secretion (PubMed:21242590). |
| Cellular Location | Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein. Cell membrane |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI1150
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