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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-CLIP1 Rabbit Monoclonal Antibody
KD-Validated Anti-CLIP1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P30622 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB3080 |
| Calculated MW | Predicted, 162 kDa , observed, 170 kDa |
| Gene Name | CLIP1 |
| Aliases | CLIP1; CAP-Gly Domain Containing Linker Protein 1; CLIP-170; CYLN1; CLIP170; CLIP; RSN; Restin (Reed-Steinberg Cell-Expressed Intermediate Filament-Associated Protein); CAP-Gly Domain-Containing Linker Protein 1; Cytoplasmic Linker Protein 170 Alpha-2; Cytoplasmic Linker Protein 1; Restin; Reed-Sternberg Intermediate Filament-Associated Protein; Cytoplasmic Linker Protein CLIP-170 |
| Immunogen | A synthesized peptide derived from CLIP170 |
| Gene ID | 6249 |
|---|---|
| Other Names | CAP-Gly domain-containing linker protein 1, Cytoplasmic linker protein 1, Cytoplasmic linker protein 170 alpha-2, CLIP-170, Reed-Sternberg intermediate filament-associated protein, Restin, CLIP1, CYLN1, RSN |
| Name | CLIP1 |
|---|---|
| Synonyms | CYLN1, RSN |
| Function | Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking. |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle. Note=Localizes to microtubule plus ends (PubMed:17889670, PubMed:21646404). Localizes preferentially to the ends of tyrosinated microtubules (By similarity). Accumulates in plasma membrane regions with ruffling and protrusions. Associates with the membranes of intermediate macropinocytic vesicles (PubMed:12433698) {ECO:0000250|UniProtKB:Q922J3, ECO:0000269|PubMed:12433698, ECO:0000269|PubMed:17889670, ECO:0000269|PubMed:21646404} |
| Tissue Location | Detected in dendritic cells (at protein level). Highly expressed in the Reed-Sternberg cells of Hodgkin disease |
Research Areas
Citations (0)
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Application Protocols
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$ 149.00
$ 499.00
Cat# AGI1157
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