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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-Carbonic anhydrase II Rabbit Monoclonal Antibody
KD-Validated Anti-Carbonic anhydrase II Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P00918 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB 3300 |
| Calculated MW | Predicted, 29 kDa , observed, 29 kDa |
| Gene Name | CA2 |
| Aliases | CA2; Carbonic Anhydrase 2; CA-II; Carbonic Anhydrase II; CAII; Carbonate Dehydratase II; Cyanamide Hydratase CA2; Carbonic Anhydrase C; EC 4.2.1.1; Car2; CAC; Epididymis Secretory Protein Li 282; Epididymis Luminal Protein 76; Carbonic Anhydrase B; Carbonic Dehydratase; EC 4.2.1.69; HEL-S-282; HEL-76; CAR2 |
| Immunogen | A synthesized peptide derived from human Carbonic anhydrase 2 |
| Gene ID | 760 |
|---|---|
| Other Names | Carbonic anhydrase 2, 4.2.1.1, Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II, Cyanamide hydratase CA2, 4.2.1.69, CA2 |
| Name | CA2 |
|---|---|
| Function | Catalyzes the reversible hydration of carbon dioxide (PubMed:11327835, PubMed:11802772, PubMed:11831900, PubMed:12056894, PubMed:12171926, PubMed:1336460, PubMed:14736236, PubMed:15300855, PubMed:15453828, PubMed:15667203, PubMed:15865431, PubMed:16106378, PubMed:16214338, PubMed:16290146, PubMed:16686544, PubMed:16759856, PubMed:16807956, PubMed:17127057, PubMed:17251017, PubMed:17314045, PubMed:17330962, PubMed:17346964, PubMed:17540563, PubMed:17588751, PubMed:17705204, PubMed:18024029, PubMed:18162396, PubMed:18266323, PubMed:18374572, PubMed:18481843, PubMed:18618712, PubMed:18640037, PubMed:18942852, PubMed:1909891, PubMed:1910042, PubMed:19170619, PubMed:19186056, PubMed:19206230, PubMed:19520834, PubMed:19778001, PubMed:7761440, PubMed:7901850, PubMed:8218160, PubMed:8262987, PubMed:8399159, PubMed:8451242, PubMed:8485129, PubMed:8639494, PubMed:9265618, PubMed:9398308). Can also hydrate cyanamide to urea (PubMed:10550681, PubMed:11015219). Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (PubMed:15990874). Essential for bone resorption and osteoclast differentiation (PubMed:15300855). Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. |
| Cellular Location | Cytoplasm. Cell membrane. Note=Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI1195
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