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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-ABHD5 Rabbit Monoclonal Antibody
KD-Validated Anti-ABHD5 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC |
|---|---|
| Primary Accession | Q8WTS1 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB 3260 |
| Calculated MW | Predicted, 39 kDa , observed, 45 kDa |
| Gene Name | ABHD5 |
| Aliases | ABHD5; Antibodyhydrolase Domain Containing 5, Lysophosphatidic Acid Acyltransferase; NCIE2; 1-Acylglycerol-3-Phosphate O-Acyltransferase ABHD5; Antibodyhydrolase Domain-Containing Protein 5; Lipid Droplet-Binding Protein CGI-58; EC 2.3.1.51; CGI-58; Antibodyhydrolase Domain Containing 5; CGI58; IECN2 |
| Immunogen | A synthesized peptide derived from human ABHD5 |
| Gene ID | 51099 |
|---|---|
| Other Names | 1-acylglycerol-3-phosphate O-acyltransferase ABHD5, 2.3.1.51, Abhydrolase domain-containing protein 5, Lipid droplet-binding protein CGI-58, ABHD5 (HGNC:21396), NCIE2 |
| Name | ABHD5 (HGNC:21396) |
|---|---|
| Synonyms | NCIE2 |
| Function | Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfer of an acyl group on a lysophosphatidic acid (PubMed:18606822). Functions preferentially with 1-oleoyl- lysophosphatidic acid followed by 1-palmitoyl-lysophosphatidic acid, 1- stearoyl-lysophosphatidic acid and 1-arachidonoyl-lysophosphatidic acid as lipid acceptor. Functions preferentially with arachidonoyl-CoA followed by oleoyl-CoA as acyl group donors (By similarity). Functions in phosphatidic acid biosynthesis (PubMed:18606822). May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2 (PubMed:16679289). Involved in keratinocyte differentiation (PubMed:18832586). Regulates lipid droplet fusion (By similarity). |
| Cellular Location | Cytoplasm. Lipid droplet {ECO:0000250|UniProtKB:Q9DBL9}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9DBL9}. Note=Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA (By similarity). |
| Tissue Location | Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons (at protein level). |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI1209
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