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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-ACADVL Rabbit Monoclonal Antibody
KD-Validated Anti-ACADVL Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P49748 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB3615 |
| Calculated MW | Predicted, 70 kDa , observed, 65 kDa |
| Gene Name | ACADVL |
| Aliases | ACADVL; Acyl-CoA Dehydrogenase Very Long Chain; VLCAD; LCACD; ACAD6; Very Long-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial; Acyl-Coenzyme A Dehydrogenase, Very Long Chain; EC 1.3.8.9; EC 1.3.99 |
| Immunogen | A synthesized peptide derived from human ACADVL/VLCAD |
| Gene ID | 37 |
|---|---|
| Other Names | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial, VLCAD, 1.3.8.9, ACADVL (HGNC:92) |
| Name | ACADVL (HGNC:92) |
|---|---|
| Function | Very long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats (PubMed:18227065, PubMed:7668252, PubMed:9461620, PubMed:9599005, PubMed:9839948). The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl- CoA (PubMed:18227065, PubMed:7668252, PubMed:9461620, PubMed:9839948). Among the different mitochondrial acyl-CoA dehydrogenases, very long- chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 12 to 24 carbons long primary chains (PubMed:21237683, PubMed:9839948). |
| Cellular Location | Mitochondrion inner membrane; Peripheral membrane protein |
| Tissue Location | Predominantly expressed in heart and skeletal muscle (at protein level). Also detected in kidney and liver (at protein level). |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 149.00
$ 499.00
Cat# AGI1225
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