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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-ATP5B Rabbit Monoclonal Antibody
KD-Validated Anti-ATP5B Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P06576 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB 3255 |
| Calculated MW | Predicted, 57 kDa , observed, 50 kDa |
| Gene Name | ATP5F1B |
| Aliases | ATP5F1B; ATP Synthase F1 Subunit Beta; ATP5B; ATPSB; ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, Beta Polypeptide; ATP Synthase Subunit Beta, Mitochondrial; ATPMB; Mitochondrial ATP Synthetase, Beta Subunit; Mitochondrial ATP Synthase Beta Subunit; Epididymis Secretory Protein Li 271; EC 3.6.3.14; EC 7.1.2.2; HEL-S-271; EC 3.6.3; HUMOP2 |
| Immunogen | A synthesized peptide derived from human ATPB |
| Gene ID | 506 |
|---|---|
| Other Names | ATP synthase F(1) complex subunit beta, mitochondrial, 7.1.2.2, ATP synthase F1 subunit beta {ECO:0000312|HGNC:HGNC:830}, ATP5F1B (HGNC:830) |
| Name | ATP5F1B (HGNC:830) |
|---|---|
| Function | Catalytic subunit beta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (Probable) (PubMed:37244256). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). With the subunit alpha (ATP5F1A), forms the catalytic core in the F(1) domain (PubMed:37244256). |
| Cellular Location | Mitochondrion inner membrane; Peripheral membrane protein {ECO:0000250|UniProtKB:P00829}; Matrix side {ECO:0000250|UniProtKB:P00829, ECO:0000269|PubMed:25168243} |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI1323
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