KD-Validated Anti-CAPG Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC, ICC |
---|---|
Primary Accession | P40121 |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 25GB3045 |
Calculated MW | Predicted, 38 kDa; observed, 38 kDa |
Gene Name | CAPG |
Aliases | CAPG; Capping Actin Protein, Gelsolin Like; MCP; AFCP; Capping Protein (Actin Filament), Gelsolin-Like; Macrophage-Capping Protein; Epididymis Secretory Protein Li 66; Actin-Regulatory Protein CAP-G; Actin Regulatory Protein CAP-G; Gelsolin-Like Capping Protein; Macrophage Capping Protein; HEL-S-66 |
Immunogen | A synthesized peptide derived from human CAPG |
Gene ID | 822 |
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Other Names | Macrophage-capping protein, Actin regulatory protein CAP-G, CAPG, AFCP, MCP |
Name | CAPG |
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Synonyms | AFCP, MCP |
Function | Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. |
Cellular Location | Nucleus. Cytoplasm Melanosome. Cell projection, lamellipodium {ECO:0000250|UniProtKB:P24452}. Cell projection, ruffle {ECO:0000250|UniProtKB:P24452}. Note=In macrophages, may be predominantly cytoplasmic. Nuclear localization was observed in fibroblasts. In macrophages, present at the membrane-cytoplasm interface. In activated macrophages, concentrated in the ruffles of the leading lamellipodia. {ECO:0000250|UniProtKB:P24452} |
Tissue Location | Macrophages and macrophage-like cells. |

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