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> home > Products > Primary Antibodies > Antibody Collections > Colon Rectum positive > KD-Validated Anti-ACADM Rabbit Monoclonal Antibody
KD-Validated Anti-ACADM Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P11310 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB3145 |
| Calculated MW | Predicted, 47 kDa; observed, 40 kDa |
| Gene Name | ACADM |
| Aliases | ACADM; Acyl-CoA Dehydrogenase Medium Chain 2 3 5; MCAD; ACAD1; Medium-Chain Specific Acyl-CoA Dehydrogenase, Mitochondrial; Acyl-Coenzyme A Dehydrogenase, C-4 To C-12 Straight Chain; Medium-Chain Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain; Medium Chain Acyl-CoA Dehydrogenase; Testicular Tissue Protein Li 7; EC 1.3.99.3; EC 1.3.8.7; EC 1.3.99 |
| Immunogen | A synthesized peptide derived from human ACADM |
| Gene ID | 34 |
|---|---|
| Other Names | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial, MCAD, 1.3.8.7, Medium chain acyl-CoA dehydrogenase, MCADH, ACADM (HGNC:89) |
| Name | ACADM (HGNC:89) |
|---|---|
| Function | Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats (PubMed:1970566, PubMed:21237683, PubMed:2251268, PubMed:8823175). The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (PubMed:2251268). Electron transfer flavoprotein (ETF) is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (PubMed:15159392, PubMed:25416781). Among the different mitochondrial acyl-CoA dehydrogenases, medium-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 6 to 12 carbons long primary chains (PubMed:1970566, PubMed:21237683, PubMed:2251268, PubMed:8823175). |
| Cellular Location | Mitochondrion matrix |
Research Areas
Citations (0)
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$ 149.00
$ 499.00
Cat# AGI1369
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