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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-Intraflagellar transport 88 Rabbit Monoclonal Antibody
KD-Validated Anti-Intraflagellar transport 88 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q13099 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB4015 |
| Calculated MW | Predicted, 94 kDa, observed, 75 kDa |
| Gene Name | IFT88 |
| Aliases | IFT88; Intraflagellar Transport 88; D13S1056E; TG737; TTC10; Recessive Polycystic Kidney Disease Protein Tg737 Homolog; Intraflagellar Transport Protein 88 Homolog; Tetratricopeptide Repeat Protein 10; Tetratricopeptide Repeat Domain 10; TPR Repeat Protein 10; Polaris Homolog; MGC26259; HTg737; Probe HTg737 (Polycystic Kidney Disease, Autosomal Recessive); Intraflagellar Transport 88 Homolog (Chlamydomonas); Intraflagellar Transport 88 Homolog; Testicular Tissue Protein Li 93; HTG737; Tg737; DAF19 |
| Immunogen | A synthesized peptide derived from human IFT88 |
| Gene ID | 8100 |
|---|---|
| Other Names | Intraflagellar transport protein 88 homolog, Recessive polycystic kidney disease protein Tg737 homolog, Tetratricopeptide repeat protein 10, TPR repeat protein 10, IFT88, TG737, TTC10 |
| Name | IFT88 |
|---|---|
| Synonyms | TG737, TTC10 |
| Function | Positively regulates primary cilium biogenesis (PubMed:17604723). Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment. |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000250|UniProtKB:Q61371}. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm {ECO:0000250|UniProtKB:Q61371}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q61371}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q61371}. Note=Colocalizes with ENTR1 and gamma- tubulin at the basal body of primary cilia (PubMed:27767179) Colocalizes with ENTR1 and pericentrin at the centrosome (PubMed:27767179). In sperm cells, localizes to the manchette, head- tail coupling apparatus and flagellum (By similarity) {ECO:0000250|UniProtKB:Q61371, ECO:0000269|PubMed:27767179} |
| Tissue Location | Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas. |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI1381
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