KD-Validated Anti-gamma Tubulin Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC |
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Primary Accession | P23258 |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 23GB4805 |
Calculated MW | Predicted, 51 kD a , observed, 48 kDa |
Gene Name | TUBG1 |
Aliases | TUBG1; Tubulin Gamma 1; TUBGCP1; TUBG; Gamma-Tubulin Complex Component 1; Tubulin, Gamma Polypeptide; Tubulin Gamma-1 Chain; GCP-1; Tubulin, Gamma 1; Gamma-1-Tubulin; CDCBM4 |
Immunogen | A synthesized peptide derived from human Tubulin gamma |
Gene ID | 7283 |
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Other Names | Tubulin gamma-1 chain, Gamma-1-tubulin, Gamma-tubulin complex component 1, GCP-1, TUBG1 (HGNC:12417), TUBG |
Name | TUBG1 (HGNC:12417) |
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Synonyms | TUBG |
Function | Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (PubMed:38305685, PubMed:38609661, PubMed:39321809). Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation (PubMed:38305685, PubMed:38609661, PubMed:39321809). The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation (PubMed:38305685, PubMed:38609661, PubMed:39321809). |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to mitotic spindle microtubules. |

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