KD-Validated Anti-KHSRP Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, FC, ICC |
|---|---|
| Primary Accession | Q92945 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB6435 |
| Calculated MW | Predicted, 73 kDa , observed , 73 kDa |
| Gene Name | KHSRP |
| Aliases | KHSRP; KH-Type Splicing Regulatory Protein; FUBP2; KSRP; FBP2; Far Upstream Element-Binding Protein; FUSE-Binding Protein; P75; Epididymis Secretory Sperm Binding Protein; KH Type-Splicing Regulatory Protein; FUSE Binding Protein 2 |
| Immunogen | A synthesized peptide derived from human KHSRP |
| Gene ID | 8570 |
|---|---|
| Other Names | Far upstream element-binding protein 2, FUSE-binding protein 2, KH type-splicing regulatory protein, KSRP, p75, KHSRP, FUBP2 |
| Name | KHSRP |
|---|---|
| Synonyms | FUBP2 |
| Function | Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue- specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs. |
| Cellular Location | Nucleus. Cytoplasm. Note=A small proportion is also found in the cytoplasm of neuronal cell bodies and dendrites. |
| Tissue Location | Detected in neural and non-neural cell lines. |

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