KD-Validated Anti-Cyclin dependent kinase 16 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC, ICC |
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Primary Accession | Q00536 |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 23GB1495 |
Calculated MW | Predicted, 56 kDa , observed, 62-68 kDa |
Gene Name | CDK16 |
Aliases | CDK16; Cyclin Dependent Kinase 16; PCTAIRE1; PCTGAIRE; PCTAIRE; PCTK1; Serine/Threonine-Protein; Kinase PCTAIRE-1; Cell Division Protein Kinase 16; PCTAIRE-Motif Protein Kinase; Cyclin-Dependent Kinase 16; EC 2.7.11.22; FLJ16665; Testis Secretory Sperm-Binding Protein Li 224n; Serine/Threonine-Protein Kinase; PCTAIRE Protein Kinase; EC 2.7.11 |
Immunogen | A synthesized peptide derived from human PCTAIRE1 |
Gene ID | 5127 |
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Other Names | Cyclin-dependent kinase 16, 2.7.11.22, Cell division protein kinase 16, PCTAIRE-motif protein kinase 1, Serine/threonine-protein kinase PCTAIRE-1, CDK16, PCTAIRE1, PCTK1 |
Name | CDK16 |
---|---|
Synonyms | PCTAIRE1, PCTK1 |
Function | Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro). |
Cellular Location | Cytoplasm. Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:Q63686} Cell membrane; Peripheral membrane protein; Cytoplasmic side. Synapse, synaptosome {ECO:0000250|UniProtKB:Q63686}. Note=Colocalizes with insulin in pancreas islets. Recruited to the cell membrane by CCNY |
Tissue Location | Detected in pancreas islets (at protein level). Detected in brain and pancreas. |

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