KD-Validated Anti-Glutamic-oxaloacetic transaminase 2 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, FC |
|---|---|
| Primary Accession | P00505 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB7985 |
| Calculated MW | Predicted, 48 kDa , observed , 43 kDa |
| Gene Name | GOT2 |
| Aliases | GOT2; Glutamic-Oxaloacetic Transaminase 2; KYAT4; Kynurenine Aminotransferase IV; MAspAT; KATIV; KAT4; Plasma Membrane-Associated Fatty Acid-Binding Protein; Glutamic-Oxaloacetic Transaminase 2, Mitochondrial; Aspartate Aminotransferase, Mitochondrial; Kynurenine--Oxoglutarate Transaminase IV; Kynurenine--Oxoglutarate Transaminase 4; Glutamate Oxaloacetate Transaminase 2; Kynurenine Aminotransferase 4; Aspartate Aminotransferase 2; Fatty Acid-Binding Protein; Aspartate Transaminase 2; Transaminase A; EC 2.6.1.1; MitAAT; FABP-1; FABPpm; Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2); EC 2.6.1.7; EC 2.6.1; MITAAT; DEE82 |
| Immunogen | A synthesized peptide derived from human GOT2 |
| Gene ID | 2806 |
|---|---|
| Other Names | Aspartate aminotransferase, mitochondrial, mAspAT, 2.6.1.1, 2.6.1.7, Fatty acid-binding protein, FABP-1, Glutamate oxaloacetate transaminase 2, Kynurenine aminotransferase 4, Kynurenine aminotransferase IV, Kynurenine--oxoglutarate transaminase 4, Kynurenine--oxoglutarate transaminase IV, Plasma membrane-associated fatty acid-binding protein, FABPpm, Transaminase A, GOT2 (HGNC:4433) |
| Name | GOT2 (HGNC:4433) |
|---|---|
| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids. |
| Cellular Location | Mitochondrion matrix. Cell membrane. Note=Exposure to alcohol promotes translocation to the cell membrane. |

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