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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   KD-Validated Antibodies   >   KD-Validated Anti-Farnesyl diphosphate synthase Rabbit Monoclonal Antibody   

KD-Validated Anti-Farnesyl diphosphate synthase Rabbit Monoclonal Antibody

Rabbit monoclonal antibody

     
  • WB - KD-Validated Anti-Farnesyl diphosphate synthase Rabbit Monoclonal Antibody AGI1583
    Western blotting analysis using anti-Farnesyl diphosphate synthase antibody (Cat#AGI1583). Total cell lysates (30 µg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-Farnesyl diphosphate synthase antibody (Cat#AGI1583, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody respectively.
    detail
  • WB - KD-Validated Anti-Farnesyl diphosphate synthase Rabbit Monoclonal Antibody AGI1583
    Western blotting analysis using anti-Farnesyl diphosphate synthase antibody (Cat#AGI1583). Farnesyl diphosphate synthase expression in wild type (WT) and farnesyl diphosphate synthase shRNA knockdown (KD) HeLa cells with 30 µg of total cell lysates. β-Tubulin serves as a loading control. The blot was incubated with anti-Farnesyl diphosphate synthase antibody (Cat#AGI1583, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody respectively.
    detail
  • FC - KD-Validated Anti-Farnesyl diphosphate synthase Rabbit Monoclonal Antibody AGI1583
    Flow cytometric analysis of Farnesyl diphosphate synthase expression in HepG2 cells using Farnesyl diphosphate synthase antibody (Cat#AGI1583, 1:2,000). Green, isotype control; red, Farnesyl diphosphate synthase.
    detail
  • ICC - KD-Validated Anti-Farnesyl diphosphate synthase Rabbit Monoclonal Antibody AGI1583
    Immunocytochemical staining of HepG2 cells with Farnesyl diphosphate synthase antibody (Cat#AGI1583, 1:1,000). Nuclei were stained blue with DAPI; Farnesyl diphosphate synthase was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 µm.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, FC, ICC
Primary Accession P14324
Reactivity Human
Clonality Monoclonal
Isotype Rabbit IgG
Clone Names 23GB1395
Calculated MW Predicted, 48 kDa, observed, 36 kDa
Gene Name FDPS
Aliases FDPS; Farnesyl Diphosphate Synthase; Farnesyl Pyrophosphate Synthetase, Dimethylallyltranstransferase, Geranyltranstransferase; (2E,6E)-Farnesyl Diphosphate Synthase; Farnesyl Pyrophosphate Synthase; FPP Synthase; FPS; Dimethylallyltranstransferase; Geranyltranstransferase; FPP Synthetase; EC 2.5.1.10; EC 2.5.1.1; KIAA1293; POROK9; FPPS
Immunogen A synthesized peptide derived from human FDPS
Additional Information
Gene ID 2224
Other Names Farnesyl pyrophosphate synthase, FPP synthase, FPS, 2.5.1.10, (2E, 6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, 2.5.1.1, Farnesyl diphosphate synthase, Geranyltranstransferase, FDPS (HGNC:3631), FPS, KIAA1293
Protein Information
Name FDPS (HGNC:3631)
Synonyms FPS, KIAA1293
Function Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
Cellular Location Cytoplasm.
Research Areas
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$ 149.00
$ 499.00
Cat# AGI1583
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