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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-NDUFA13 Rabbit Monoclonal Antibody
KD-Validated Anti-NDUFA13 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, ICC |
|---|---|
| Primary Accession | Q9P0J0 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB600 |
| Calculated MW | Predicted, 17 kDa , observed , 17 kDa |
| Gene Name | NDUFA13 |
| Aliases | NADH:Ubiquinone Oxidoreductase Subunit A13; GRIM-19; GRIM19; CGI-39; CDA016; B16.6; Gene Associated With Retinoic And Interferon-Induced Mortality 19 Protein; Gene Associated With Retinoic And IFN-Induced Mortality 19 Protein; NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Subunit 13; NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, 13; NADH-Ubiquinone Oxidoreductase B16.6 Subunit; Cell Death Regulatory Protein GRIM-19; Complex I B16.6 Subunit; Complex I-B16.6; CI-B16.6; Cell Death-Regulatory Protein GRIM19; MC1DN28 |
| Immunogen | A synthesized peptide derived from human GRIM19 |
| Gene ID | 51079 |
|---|---|
| Other Names | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, Cell death regulatory protein GRIM-19, Complex I-B16.6, CI-B16.6, Gene associated with retinoic and interferon-induced mortality 19 protein, GRIM-19, Gene associated with retinoic and IFN-induced mortality 19 protein, NADH-ubiquinone oxidoreductase B16.6 subunit, NDUFA13, GRIM19 |
| Name | NDUFA13 |
|---|---|
| Synonyms | GRIM19 |
| Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis (PubMed:27626371). Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:27626371). Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes (PubMed:15753091). |
| Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. Nucleus Note=Localizes mainly in the mitochondrion (PubMed:12628925). May be translocated into the nucleus upon IFN/RA treatment |
| Tissue Location | Widely expressed, with highest expression in heart, skeletal muscle, liver, kidney and placenta. In intestinal mucosa, down-regulated in areas involved in Crohn disease and ulcerative colitis. |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI1617
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