KD-Validated Anti-PCBD1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, ICC |
---|---|
Primary Accession | P61457 |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 24GB785 |
Calculated MW | Predicted, 12 kDa , observed , 12 kDa |
Gene Name | PCBD1 |
Aliases | Pterin-4 Alpha-Carbinolamine Dehydratase 1; PCD; DCOH; PCBD; 6-Pyruvoyl-Tetrahydropterin Synthase/Dimerization Cofactor Of Hepatocyte Nuclear Factor 1 Alpha (TCF1); Pterin-4 Alpha-Carbinolamine Dehydratase/Dimerization Cofactor Of Hepatocyte Nuclear Factor 1 Alpha; Phenylalanine Hydroxylase-Stimulating Protein; 4-Alpha-Hydroxy-Tetrahydropterin Dehydratase; Pterin-4-Alpha-Carbinolamine Dehydratase; Dimerizing Cofactor For HNF1; EC 4.2.1.96; PHS; Pterin-4 Alpha-Carbinolamine Dehydratase/Dimerization Cofactor Of Hepatocyte Nuclear Factor 1 Alpha (TCF1); Pterin-4a-Carbinolamine Dehydratase (Dimerization Cofactor Of Hepatic Nuclear Factor 1-Alpha); Dimerization Cofactor Of Hepatocyte Nuclear Factor 1-Alpha; Pterin-4-Alpha Carbinolamine Dehydratase; Pterin Carbinolamine Dehydratase; Dimerization Cofactor Of HNF1; DCoH |
Immunogen | A synthesized peptide derived from human PCBD1 |
Gene ID | 5092 |
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Other Names | Pterin-4-alpha-carbinolamine dehydratase, PHS, 4.2.1.96, 4-alpha-hydroxy-tetrahydropterin dehydratase, Dimerization cofactor of hepatocyte nuclear factor 1-alpha, DCoH, Dimerization cofactor of HNF1, Phenylalanine hydroxylase-stimulating protein, Pterin carbinolamine dehydratase, PCD, PCBD1, DCOH, PCBD |
Name | PCBD1 |
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Synonyms | DCOH, PCBD |
Function | Involved in tetrahydrobiopterin biosynthesis (By similarity). Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription (By similarity). Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity (By similarity). Also acts as a coactivator for HNF1B-dependent transcription (PubMed:24204001). |
Cellular Location | Cytoplasm. Nucleus. Note=Recruited to the nucleus through the interaction with HNF1B. |

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