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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-Peroxiredoxin 6 Rabbit Monoclonal Antibody
KD-Validated Anti-Peroxiredoxin 6 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
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- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P30041 |
| Reactivity | Rat, Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB910 |
| Calculated MW | Predicted, 25 kDa , observed , 25 kDa |
| Gene Name | PRDX6 |
| Aliases | Peroxiredoxin 6; AiPLA2; NSGPx; AOP2; KIAA0106; 1-Cys; PRX; P29; Acidic Calcium-Independent Phospholipase A2; Lysophosphatidylcholine Acyltransferase 5; Glutathione-Dependent Peroxiredoxin; Non-Selenium Glutathione Peroxidase; Red Blood Cells Page Spot 12; Lyso-PC Acyltransferase 5; LPC Acyltransferase 5; Antioxidant Protein 2; Liver 2D Page Spot 40; 1-Cys Peroxiredoxin; Peroxiredoxin-6; 24 KDa Protein; 1-Cys PRX; MGC46173; LPCAT-5; Epididymis Secretory Sperm Binding Protein Li 128m; EC 1.11.1.27; EC 1.11.1.15; EC 2.3.1.23; HEL-S-128m; EC 3.1.1.4 |
| Immunogen | A synthesized peptide derived from human PRDX6 |
| Gene ID | 9588 |
|---|---|
| Other Names | Peroxiredoxin-6, 1.11.1.27, 1-Cys peroxiredoxin, 1-Cys PRX, 24 kDa protein, Acidic calcium-independent phospholipase A2, aiPLA2, 3.1.1.4, Antioxidant protein 2, Glutathione-dependent peroxiredoxin, Liver 2D page spot 40, Lysophosphatidylcholine acyltransferase 5, LPC acyltransferase 5, LPCAT-5, Lyso-PC acyltransferase 5, 2.3.1.23, Non-selenium glutathione peroxidase, NSGPx, Red blood cells page spot 12, PRDX6, AOP2, KIAA0106 |
| Name | PRDX6 |
|---|---|
| Synonyms | AOP2, KIAA0106 |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (PubMed:10893423, PubMed:9497358). Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides (PubMed:10893423). Also has phospholipase activity, can therefore either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity) (PubMed:10893423, PubMed:26830860). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH (PubMed:10893423). Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis (PubMed:10893423). Exhibits acyl-CoA-dependent lysophospholipid acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3- phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero- 3-phosphocholine or PC) (PubMed:26830860). Shows a clear preference for LPC as the lysophospholipid and for palmitoyl CoA as the fatty acyl substrate (PubMed:26830860). |
| Cellular Location | Cytoplasm. Lysosome {ECO:0000250|UniProtKB:O35244}. Note=Also found in lung secretory organelles (lamellar bodies). {ECO:0000250|UniProtKB:O35244} |
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$ 149.00
$ 499.00
Cat# AGI1636
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