KD-Validated Anti-Peroxiredoxin 3 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC, ICC |
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Primary Accession | P30048 |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 24GB935 |
Calculated MW | Predicted, 28 kDa , observed , 24 kDa |
Gene Name | PRDX3 |
Aliases | Peroxiredoxin 3; AOP-1; Antioxidant Protein 1; SP-22; MER5; AOP1; Thioredoxin-Dependent Peroxide Reductase, Mitochondrial; Thioredoxin-Dependent Peroxiredoxin 3; Protein MER5 Homolog; Peroxiredoxin III; Prx-III; HBC189; Epididymis Secretory Sperm Binding Protein; Peroxiredoxin-3; EC 1.11.1.24; EC 1.11.1.15; PRO1748; SCAR32; PPPCD |
Immunogen | A synthesized peptide derived from human Peroxiredoxin 3 |
Gene ID | 10935 |
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Other Names | Thioredoxin-dependent peroxide reductase, mitochondrial, 1.11.1.24, Antioxidant protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog, Thioredoxin-dependent peroxiredoxin 3, PRDX3, AOP1 |
Name | PRDX3 |
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Synonyms | AOP1 |
Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides (PubMed:17707404, PubMed:29438714, PubMed:33889951, PubMed:7733872). Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol (PubMed:12492477). Required for the maintenance of physical strength (By similarity). |
Cellular Location | Mitochondrion. Cytoplasm. Early endosome. Note=Localizes to early endosomes in a RPS6KC1-dependent manner. |

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