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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-Prolyl Endopeptidase Like Rabbit Monoclonal Antibody
KD-Validated Anti-Prolyl Endopeptidase Like Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q4J6C6 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB990 |
| Calculated MW | Predicted, 84 kDa , observed , 70 kDa |
| Gene Name | PREPL |
| Aliases | Prolyl Endopeptidase Like; Prolyl Endopeptidase-Like; KIAA0436; Putative Prolyl Oligopeptidase; Prolylendopeptidase-Like; EC 3.4.21.83; EC 3.4.21.-; EC 3.4.21; CMS22 |
| Immunogen | A synthesized peptide derived from human PREPL |
| Gene ID | 9581 |
|---|---|
| Other Names | Prolyl endopeptidase-like, 3.4.21.-, Prolylendopeptidase-like, PREPL, KIAA0436 |
| Name | PREPL |
|---|---|
| Synonyms | KIAA0436 |
| Function | Serine peptidase whose precise substrate specificity remains unclear (PubMed:16143824, PubMed:16385448, PubMed:28726805). Does not cleave peptides after a arginine or lysine residue (PubMed:16143824). Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex (PubMed:23321636). May play a role in the regulation of synaptic vesicle exocytosis (PubMed:24610330). |
| Cellular Location | Cytoplasm, cytosol. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q8C167}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8C167}. Golgi apparatus {ECO:0000250|UniProtKB:Q8C167}. Nucleus Note=Co-localizes with AP-1 in the trans-Golgi network (By similarity) Co-localizes with MAP2 and ACTB on the cytoskeleton (By similarity) Co-localizes with STX6 and GOSR2 at the Golgi apparatus (By similarity). {ECO:0000250|UniProtKB:Q8C167} |
| Tissue Location | Expressed in pyramidal neurons of the temporal cortex and neocortex (at protein level) (PubMed:23485813). Widely expressed (PubMed:15913950, PubMed:16385448). Expressed at higher level in brain, skeletal muscle, heart and kidney (PubMed:15913950, PubMed:16385448). Expressed at the endplates in the neuromuscular junction (PubMed:24610330). |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI1641
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