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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-Retinoic Acid Receptor beta Rabbit Monoclonal Antibody
KD-Validated Anti-Retinoic Acid Receptor beta Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P10826 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB1045 |
| Calculated MW | Predicted, 50 kDa ; Observed , 55 kDa |
| Gene Name | RARB |
| Aliases | Retinoic Acid Receptor Beta; RAR-Beta; NR1B2; HAP; RARbeta; RRB2; Nuclear Receptor Subfamily 1 Group B Member 2; HBV-Activated Protein; RAR-Epsilon; Retinoic Acid Receptor, Beta Polypeptide; Hepatitis B Virus Activated Protein; Retinoic Acid Receptor, Beta; RARbeta1; MCOPS12 |
| Immunogen | A synthesized peptide derived from human Retinoic Acid Receptor beta |
| Gene ID | 5915 |
|---|---|
| Other Names | Retinoic acid receptor beta, RAR-beta, HBV-activated protein, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon, RARB, HAP, NR1B2 |
| Name | RARB |
|---|---|
| Synonyms | HAP, NR1B2 |
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors (PubMed:12554770). The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element (PubMed:29021580). In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity). |
| Cellular Location | Nucleus. Cytoplasm [Isoform Beta-2]: Nucleus. |
| Tissue Location | Expressed in aortic endothelial cells (at protein level). |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 149.00
$ 499.00
Cat# AGI1647
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