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> home > Products > Primary Antibodies > Antibody Collections > SARS-Human interaction partners > KD-Validated Anti-Ribophorin I Rabbit Monoclonal Antibody
KD-Validated Anti-Ribophorin I Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC |
|---|---|
| Primary Accession | P04843 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB1090 |
| Calculated MW | Predicted, 69 kDa , observed , 69 kDa |
| Gene Name | RPN1 |
| Aliases | Ribophorin I; OST1; Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit 1; Oligosaccharyltransferase Complex Subunit (Non-Catalytic); Ribophorin-1; RPN-I; Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase 67 KDa Subunit; Dolichyl-Diphosphooligosaccharide-Protein Glycosyltransferase 67 KDa Subunit; Oligosaccharyltransferase 1 Homolog (S. Cerevisiae); Oligosaccharyltransferase 1 Homolog; EC 2.4.1.119; RBPH1 |
| Immunogen | A synthesized peptide derived from human PRibophorin I |
| Gene ID | 6184 |
|---|---|
| Other Names | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit, Ribophorin I, RPN-I, Ribophorin-1, RPN1 (HGNC:10381) |
| Name | RPN1 (HGNC:10381) |
|---|---|
| Function | Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:31831667). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:E2RQ08}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:E2RQ08}. Melanosome Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Tissue Location | Expressed in all tissues tested. |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI1651
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