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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-RBBP4 Rabbit Monoclonal Antibody
KD-Validated Anti-RBBP4 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q09028 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB1240 |
| Calculated MW | Predicted, 48 kDa , observed , 52 kDa |
| Gene Name | RBBP4 |
| Aliases | RB Binding Protein 4, Chromatin Remodeling Factor; Retinoblastoma-Binding Protein 4; RbAp48; NURF55; Lin-53; Nucleosome-Remodeling Factor Subunit RBAP48; Chromatin Assembly Factor I P48 Subunit; Chromatin Assembly Factor 1 Subunit C; Retinoblastoma-Binding Protein P48; Histone-Binding Protein RBBP4; CAF-I 48 KDa Subunit; CAF-1 Subunit C; CAF-I P48; RBBP-4; Chromatin Assembly Factor/CAF-1 P48 Subunit; Retinoblastoma Binding Protein 4; MSI1 Protein Homolog; RBAP48 |
| Immunogen | A synthesized peptide derived from human RbAp48 |
| Gene ID | 5928 |
|---|---|
| Other Names | Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, CAF-1 subunit C, Chromatin assembly factor I p48 subunit, CAF-I 48 kDa subunit, CAF-I p48, Nucleosome-remodeling factor subunit RBAP48, Retinoblastoma-binding protein 4, RBBP-4, Retinoblastoma-binding protein p48, RBBP4, RBAP48 |
| Name | RBBP4 |
|---|---|
| Synonyms | RBAP48 |
| Function | Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA (PubMed:10866654). Component of the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair (PubMed:8858152). Component of the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression (PubMed:9150135). Component of the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling (PubMed:16428440, PubMed:28977666, PubMed:39460621). Component of the PRC2 complex, which promotes repression of homeotic genes during development (PubMed:29499137, PubMed:31959557). Component of the NURF (nucleosome remodeling factor) complex (PubMed:14609955, PubMed:15310751). |
| Cellular Location | Nucleus. Chromosome, telomere. Note=Localizes to chromatin as part of the PRC2 complex. |
| Tissue Location | Expressed in neuroblastoma cells. |
Research Areas
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Application Protocols
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$ 149.00
$ 499.00
Cat# AGI1664
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