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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-SCARB1 Rabbit Monoclonal Antibody
KD-Validated Anti-SCARB1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, ICC |
|---|---|
| Primary Accession | Q8WTV0 |
| Reactivity | Rat, Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB1395 |
| Calculated MW | Predicted, 61 kDa , observed, 75 kDa |
| Gene Name | SCARB1 |
| Aliases | SCARB1; Scavenger Receptor Class B Member 1; CLA-1; SR-BI; SRB1; CLA1; CD36L1; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor)-Like 1; CD36 And LIMPII Analogous 1; Collagen Type I Receptor, Thrombospondin Receptor-Like 1; Scavenger Receptor Class B, Member 1; Scavenger Receptor Class B Type III; CD36 Antigen-Like 1; CD36 Antigen; HDLQTL6; HDLCQ6 |
| Immunogen | A synthesized peptide derived from human Scavenging Receptor SR-BI |
| Gene ID | 949 |
|---|---|
| Other Names | Scavenger receptor class B member 1, SRB1, CD36 and LIMPII analogous 1, CLA-1, CD36 antigen-like 1, Collagen type I receptor, thrombospondin receptor-like 1, SR-BI, CD36, SCARB1, CD36L1, CLA1 |
| Name | SCARB1 |
|---|---|
| Synonyms | CD36L1, CLA1 |
| Function | Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed:12016218). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Membrane, caveola {ECO:0000250|UniProtKB:Q61009}; Multi-pass membrane protein Note=Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae |
| Tissue Location | Widely expressed. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 149.00
$ 499.00
Cat# AGI1679
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