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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-TFAP2A Rabbit Monoclonal Antibody
KD-Validated Anti-TFAP2A Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P05549 |
| Reactivity | Rat, Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB2485 |
| Calculated MW | Predicted, 48 kDa , observed , 48 kDa |
| Gene Name | TFAP2A |
| Aliases | TFAP2A; Transcription Factor AP-2 Alpha; AP-2; AP-2alpha; AP2TF; TFAP2; Transcription Factor AP-2 Alpha (Activating Enhancer Binding Protein 2 Alpha); Activating Enhancer-Binding Protein 2-Alpha; Transcription Factor AP-2-Alpha; AP-2 Transcription Factor; Activator Protein 2; Transcription Factor AP-2 Alpha (Activating Enhancer-Binding Protein 2 Alpha); AP2-Alpha; BOFS |
| Immunogen | A synthesized peptide derived from human AP2 alpha |
| Gene ID | 7020 |
|---|---|
| Other Names | Transcription factor AP-2-alpha, AP2-alpha, AP-2 transcription factor, Activating enhancer-binding protein 2-alpha, Activator protein 2, AP-2, TFAP2A, AP2TF, TFAP2 |
| Name | TFAP2A |
|---|---|
| Synonyms | AP2TF, TFAP2 |
| Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. |
| Cellular Location | Nucleus. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 149.00
$ 499.00
Cat# AGI1731
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