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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-NK2 Homeobox 1 Rabbit Monoclonal Antibody
KD-Validated Anti-NK2 Homeobox 1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC |
|---|---|
| Primary Accession | P43699 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB5440 |
| Calculated MW | Predicted, 39 kDa, observed, 42 kDa |
| Gene Name | NKX2-1 |
| Aliases | NKX2-1; NK2 Homeobox 1; TTF-1; TTF1; Thyroid Transcription Factor 1; NKX2A; TITF1; Thyroid-Specific Enhancer-Binding Protein; Homeobox Protein NK-2 Homolog A; Homeobox Protein Nkx-2.1; Thyroid Nuclear Factor 1; T/EBP; BCH; NK-2 Homolog A; Benign Chorea; NKX2.1; NMTC1; NK-2; TEBP; BHC |
| Immunogen | A synthesized peptide derived from human TTF1 |
| Gene ID | 7080 |
|---|---|
| Other Names | Homeobox protein Nkx-2.1, Homeobox protein NK-2 homolog A, Thyroid nuclear factor 1, Thyroid transcription factor 1, TTF-1, Thyroid-specific enhancer-binding protein, T/EBP, NKX2-1 (HGNC:11825), NKX2A, TITF1, TTF1 |
| Name | NKX2-1 (HGNC:11825) |
|---|---|
| Synonyms | NKX2A, TITF1, TTF1 |
| Function | Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:P50220}. |
| Tissue Location | Thyroid and lung. |
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$ 149.00
$ 499.00
Cat# AGI1889
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