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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-Argininosuccinate Lyase Mouse Monoclonal Antibody
KD-Validated Anti-Argininosuccinate Lyase Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P04424 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB6585 |
| Calculated MW | Predicted, 52 kDa, observed, 45 kDa |
| Gene Name | ASL |
| Aliases | ASL; Argininosuccinate Lyase; ASAL; Arginosuccinase; EC 4.3.2.1; Argininosuccinase |
| Immunogen | Recombinant protein of human ASL |
| Gene ID | 435 |
|---|---|
| Other Names | Argininosuccinate lyase, ASAL, 4.3.2.1, Arginosuccinase, ASL |
| Name | ASL |
|---|---|
| Function | Catalyzes the reversible cleavage of L-argininosuccinate to fumarate and L-arginine, an intermediate step reaction in the urea cycle mostly providing for hepatic nitrogen detoxification into excretable urea as well as de novo L-arginine synthesis in nonhepatic tissues (PubMed:11747432, PubMed:11747433, PubMed:22081021, PubMed:2263616, PubMed:9045711). Essential regulator of intracellular and extracellular L-arginine pools. As part of citrulline-nitric oxide cycle, forms tissue-specific multiprotein complexes with argininosuccinate synthase ASS1, transport protein SLC7A1 and nitric oxide synthase NOS1, NOS2 or NOS3, allowing for cell-autonomous L- arginine synthesis while channeling extracellular L-arginine to nitric oxide synthesis pathway (PubMed:22081021). |
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$ 149.00
$ 499.00
Cat# AGI1949
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