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KD-Validated Anti-CNP Mouse Monoclonal Antibody

Mouse monoclonal antibody

     
  • WB - KD-Validated Anti-CNP Mouse Monoclonal Antibody AGI2005
    Western blotting analysis using anti-CNP antibody (Cat#AGI2005). Total cell lysates (30 µg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-CNP antibody (Cat#AGI2005, 1:5,000) and HRP-conjugated goat anti-mouse secondary antibody respectively.
    detail
  • WB - KD-Validated Anti-CNP Mouse Monoclonal Antibody AGI2005
    Western blotting analysis using anti-CNP antibody (Cat#AGI2005). CNP expression in wild-type (WT) and CNP shRNA knockdown (KD) HT-1080 cells with 20 µg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-CNP antibody (Cat#AGI2005, 1:5,000) and HRP-conjugated goat anti-mouse secondary antibody respectively.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P09543
Reactivity Human
Clonality Monoclonal
Isotype Mouse IgG1/Kappa
Clone Names 24GB8575
Calculated MW Predicted, 48 kDa, observed, 40 kDa
Gene Name CNP
Aliases CNP; 2',3'-Cyclic Nucleotide 3' Phosphodiesterase; 2',3'-Cyclic-Nucleotide 3'-Phosphodiesterase; EC 3.1.4.37; CNPase; 2', 3' Cyclic Nucleotide 3' Phosphohydrolase; HLD20; CNP1
Immunogen KLH conjugated synthetic peptide derived from human CNPase
Additional Information
Gene ID 1267
Other Names 2', 3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, CNPase, 3.1.4.37, CNP (HGNC:2158)
Protein Information
Name CNP (HGNC:2158)
Function Catalyzes the formation of 2'-nucleotide products from 2',3'- cyclic substrates (By similarity). May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin (By similarity).
Cellular Location Membrane {ECO:0000250|UniProtKB:P16330}; Lipid- anchor {ECO:0000250|UniProtKB:P16330}. Melanosome. Note=Firmly bound to membrane structures of brain white matter. {ECO:0000250|UniProtKB:P16330}
Research Areas
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$ 149.00
$ 499.00
Cat# AGI2005
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