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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-CAPZA1 Mouse Monoclonal Antibody
KD-Validated Anti-CAPZA1 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC |
|---|---|
| Primary Accession | P52907 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB7905 |
| Calculated MW | Predicted, 33 kDa, observed, 36 kDa |
| Gene Name | CAPZA1 |
| Aliases | CAPZA1; Capping Actin Protein Of Muscle Z-Line Subunit Alpha 1; CAPPA1; Capping Protein (Actin Filament) Muscle Z-Line, Alpha 1; Capping Actin Protein Of Muscle Z-Line Alpha Subunit 1; F-Actin-Capping Protein Subunit Alpha-1; CapZ Alpha-1; Cap Z; CAPZ; CAZ1 |
| Immunogen | Recombinant protein of human CAPZA1 |
| Gene ID | 829 |
|---|---|
| Other Names | F-actin-capping protein subunit alpha-1, CapZ alpha-1, CAPZA1 (HGNC:1488) |
| Name | CAPZA1 (HGNC:1488) |
|---|---|
| Function | F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions (PubMed:22891260). Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A0PFK5} |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI2006
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