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> home > Products > Primary Antibodies > Antibody Collections > Thyroid gland positive > KD-Validated Anti-BDH2 Mouse Monoclonal Antibody
KD-Validated Anti-BDH2 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC |
|---|---|
| Primary Accession | Q9BUT1 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2a |
| Clone Names | 24GB7910 |
| Calculated MW | Predicted, 27 kDa, observed, 27 kDa |
| Gene Name | BDH2 |
| Aliases | BDH2; 3-Hydroxybutyrate Dehydrogenase 2; SDR15C1; PRO20933; UCPA-OR; UNQ6308; DHRS6; Short Chain Dehydrogenase/Reductase Family 15C Member 1; Dehydrogenase/Reductase SDR Family Member 6; 3-Hydroxybutyrate Dehydrogenase, Type 2; (R)-Beta-Hydroxybutyrate Dehydrogenase; 4-Oxo-L-Proline Reductase; Oxidoreductase UCPA; FLJ13261; Short Chain Dehydrogenase/Reductase Family 15C, Member 1; Dehydrogenase/Reductase (SDR Family) Member 6; 3-Hydroxybutyrate Dehydrogenase Type 2; R-Beta-Hydroxybutyrate Dehydrogenase; EC 1.1.1.104; EC 1.1.1.30; EC 1.1.1.-; EFA6R |
| Immunogen | Recombinant protein of human BDH2 |
| Gene ID | 56898 |
|---|---|
| Other Names | Dehydrogenase/reductase SDR family member 6, 1.1.1.-, (R)-beta-hydroxybutyrate dehydrogenase, 3-hydroxybutyrate dehydrogenase type 2, 1.1.1.30, 4-oxo-L-proline reductase, 1.1.1.104, Oxidoreductase UCPA, Short chain dehydrogenase/reductase family 15C member 1, BDH2 {ECO:0000303|PubMed:35150746, ECO:0000312|HGNC:HGNC:32389} |
| Name | BDH2 {ECO:0000303|PubMed:35150746, ECO:0000312|HGNC:HGNC:32389} |
|---|---|
| Function | NAD(H)-dependent dehydrogenase/reductase with a preference for cyclic substrates (By similarity) (PubMed:35150746). Catalyzes stereoselective conversion of 4-oxo-L-proline to cis-4-hydroxy-L- proline, likely a detoxification mechanism for ketoprolines (PubMed:35150746). Mediates the formation of 2,5-dihydroxybenzoate (2,5-DHBA), a siderophore that chelates free cytoplasmic iron and associates with LCN2, thereby regulating iron transport and homeostasis while protecting cells against free radical-induced oxidative stress. The iron-siderophore complex is imported into mitochondria, providing an iron source for mitochondrial metabolic processes in particular heme synthesis (By similarity). May act as a 3-hydroxybutyrate dehydrogenase (PubMed:16380372). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Detected in liver (at protein level). |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI2007
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