KD-Validated Anti-CMPK1 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC |
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Primary Accession | P30085 |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG1 |
Clone Names | 24GB7965 |
Calculated MW | Predicted, 22 kDa, observed, 20 kDa |
Gene Name | CMPK1 |
Aliases | CMPK1; Cytidine/Uridine Monophosphate Kinase 1; UMP-CMP Kinase; UMP/CMP Kinase; UMP-CMPK; CMPK; Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic; Uridine Monophosphate/Cytidine Monophosphate Kinase; Nucleoside-Diphosphate Kinase; Deoxycytidylate Kinase; Cytidylate Kinase; DCMP Kinase; EC 2.7.4.14; UMPK; CMK; UMK; CK; Cytidine Monophosphate Kinase; Uridine Monophosphate Kinase; EC 2.7.4.6; UMP/CMPK; EC 2.7.4; UCK |
Immunogen | Recombinant protein of human CMPK1 |
Gene ID | 51727 |
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Other Names | UMP-CMP kinase {ECO:0000255|HAMAP-Rule:MF_03172}, 2.7.4.14 {ECO:0000255|HAMAP-Rule:MF_03172}, Deoxycytidylate kinase {ECO:0000255|HAMAP-Rule:MF_03172}, CK {ECO:0000255|HAMAP-Rule:MF_03172}, dCMP kinase {ECO:0000255|HAMAP-Rule:MF_03172}, Nucleoside-diphosphate kinase {ECO:0000255|HAMAP-Rule:MF_03172}, 2.7.4.6 {ECO:0000255|HAMAP-Rule:MF_03172}, Uridine monophosphate/cytidine monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03172}, UMP/CMP kinase {ECO:0000255|HAMAP-Rule:MF_03172}, UMP/CMPK {ECO:0000255|HAMAP-Rule:MF_03172}, CMPK1 {ECO:0000255|HAMAP-Rule:MF_03172} |
Name | CMPK1 {ECO:0000255|HAMAP-Rule:MF_03172} |
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Function | Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity. |
Cellular Location | Nucleus {ECO:0000255|HAMAP-Rule:MF_03172, ECO:0000269|PubMed:10462544, ECO:0000269|PubMed:11912132}. Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03172, ECO:0000269|PubMed:10462544, ECO:0000269|PubMed:11912132}. Note=Predominantly cytoplasmic, less than 15% nuclear. |
Tissue Location | Ubiquitously expressed. |

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